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p30

An actin-bundling protein from Dictyostelium discoideum present in filopodia (Fechheimer, 1987), contact regions  (Fechheimer et al, 1994) phagosomes (Rezabek et al, 1997; Furukawa & Fechheimer, 1994), the cleavage furrow and the contractile vacuole (Haugwitz et al, 1994).

References:-

Furukawa, R. & Fechheimer, M. (1996) Role of the Dictyostelium 30 kDa protein in actin bundle formation., Biochemistry. 35, 7224-7232.

Schlatterer, C. & Malchow, D. (1993) Intracellular guanosine-5'-0-(3-thiotrisphosphate) blocks chemotactic motility of Dictyostelium discoideum amoebae, Cell Mot.Cytoskel. 25, 298-307.

Fechheimer, M., Murdock, D., Carney, M. & Glover, C. V. C. (1991) Isolation and sequenceing of cDNA clones encoding the Dictyostelium discoideum 30,000-dalton actin bundling protein, J.Biol.Chem. 266, 2883-2889.

Fechheimer, M. (1987) The Dictyostelium discoideum 30,00-Dalton protein is an actin filament-bundling protein that is selectively present in filopodia, J.Cell Biol. 104, 1539-1551.

Rezabek, B. L., Rodriguez-Paris, J. M., Cardelli, J. A. & Chia, C. P. (1997) Phagosomal proteins of Dictyostelium discoideum, J.Euk.Microbiol. 44, 284-292.

Haugwitz, M., Noegel, A. A., Karakesisoglou, J. & Schleicher, M. (1994) Dictyostelium amoebae that lack G-actin sequestering profilins show defects in F-actin content, cytokinesis and development., Cell. 79, 303-314.

Furukawa, R. & Fechheimer, M. (1994) Differential localization of a-actinin and the 30 kD actin-bundling protein in the cleavage furrow, phagocytic cup, and contractile vacuole of Dictyostelium discoideum, Cell Motility and Cytoskeleton. 29, 46-56.

Fechheimer, M., Ingalls, H. M., Furukawa, R. & Luna, E. J. (1994) Association of the Dictyostelium 30 kDa actin bundling protein with contact regions, J. Cell Science. 107, 2393-2401.

 Zigmond, S. H., Furukawa, R. & Fechheimer, M. (1992) Inhibition of Actin Filament Depolymerization by the Dictyostelium 30,000-D Actin-bundling Protein, J.Cell Biol. 119, 559-567.

 
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