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A c75kDa kelch repeat containing actin-binding protein expressed predominantly in brain (Chen et al, 2002). Actinfilin has the same overall structure as mayven, kelch, and Enc-1, other actin-binding proteins.  At the N terminus there is a BTB or POZ domain through which actinfilin self associates.


Chen, Y., Derin, R., Petralia, R. S. & Li, M. (2002) Actinfilin, a brain-specific actin-binding protein in postsynaptic density. J. Biol. Chem. 277, 30495-30501.

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