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Ezrin (cytovillin)

A member of the ERM (Ezrin, Radixin, Moesin) group of proteins (see ERM page) whose C terminal half (approximately) is homologous to the membrane associated  region of the band 4.1 super-family (Fig 1a).  Ezrin associates with a number of membranous proteins such as CD44, CD43 at the cytoplasmic face of the plasma-membrane. It is especially abundant in the placenta. 

References:-

Bretscher, A. (1999). "Regulation of cortical structure by ezrin-radixin-moesin protein family." Curr.Op.Cell Biol. 11, 109-116.

Crepaldi, T., A. Gautreau, et al. (1997). "Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells." J.Cell Biol. 138(2), 423-434.

Mangeat, P., Roy, C. & Martin, M. (1999). "ERM proteins in cell adhesion and membrane dynamics." Trends Cell Biology 9, 187-192.

 

Tsukita, S., Yonemura,S. & Tsukita, S. (1997)."ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transduction." Curr.Biol. 9, 70-75.

 
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