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NPA (naphthylphthalamic acid binding protein)


Previously known to co-localise with the F-actin cytoskeleton in plants (Cox & Muday, 1994), NPA was then found to bind to F-actin columns (Hu et al, 2000), it therefore appears that NPA is an actin binding protein, however the possibility that it binds actin via a third party cannot yet be ruled out.


Butler, J. H., Hu, S., Brady, S. R., Dixon, M. W. & Muday, G. K. (1998) In vitro and in vivo evidence for actin association of the naphthylphthalamic acid-binding protein from zucchini hypocotyls., Plant J. 13, 291-301.

Cox, D.N, and Muday, G.K. (1994). "NPA binding activity is peripheral to the plasma membrane and is associated with the cytoskeleton." Plant Cell 6, 1941-1953.

Hu, S., Brady, S.R., Kovar, D.R., Staiger, C.J., Clark, G.B., Roux, S.J. and Muday, G.K. (2000). "Identification of plant actin-binding proteins by F-actin affinity chromatography." Plant J. 24(1), 127-137.

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