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Sla2p (End4p, Mop2p)

A 110kDa actin-organising protein identified first in Saccharomyces cerevisiae (Holtzman et al, 1993).

References:-

Critchley, D. R. (2000) Focal adhesions - the cytoskeletal connection., Curr.Op.Cell Biol. 12, 133-139.

Engqvist-Goldstein, A.E.Y., Kessels, M.M., Chopra, V.S., Hayden, M.R. & Drubin, D.G. (1999). "An actin binding protein of the Sla2/Huntington Interacting Protein 1 family is a novel component of clathrin-coated pits and vesicles." J.Cell Biol. 147(7), 1503-1518.

Holtzman, D. A., Yang, S. & Drubin, D. G. (1993) Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae, J.Cell Biol. 122, 635-644.

Mulholland, J., Wesp, A., Riezman, H. & Botstein, D. (1997) Yeast actin cytoskeleton mutants accumulate a new class of golgi-derived secretory vesicle, Mol.Biol.Cell. 8.

 
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