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An actin binding protein composed of tandem ADF homology domains that sequesters actin monomers.


Goode, B. L., Drubin, D. G. & Lappalainen, P. (1998) Regulation of the cortical actin cytoskeleton in budding yeast by twinfilin, a ubiquitous actin monomer sequestering protein. J.Cell Biol. 142, 723-733.

Palmgren, S., Ojala, P. J., Wear, M. A., Cooper, J. A. & Lappalainen, P. (2001) Interactions with PIP2, ADP-actin monomers, and capping protein regulate the activity and localization of yeast twinfilin. J. Cell Biol. 155, 251-260.

Palmgren, S., Vartiainen, M. & Lappalainen, P. (2002) Twinfilin, a molecular mailman for actin monomers. J. Cell Sci. 115, 881-886.

Wahlstrom, G., Vartiainen, M., Yamamoto, L., Mattila, P. K., Lappalainen, P. & Heino, T. I. (2001) Twinfilin is required for actin-dependent developmental processes in Drosophila. J.Cell Biol. 155, 787-795.

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