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 Peculiar amongst their famously celibate brethren, Sappinia is believed to be sexual (Goodfellow et al, 1974).  A single case of amoebic encephalitis caused by an amoeba identified on morphological grounds as being Sappinia diploidea (Gelman et al, 2001).  This patient survived the infection having been treated with the antibiotic azithromycin 250 mg/d for 31 weeks, pentamine 300 mg/d for 6weeks, intraconazole 200 mg twice daily and flucytosine 2.75g four times a day.  However, its not known if the patient would have survived without the treatment.  Sappinia has been isolatd from faeces from cow (Goodfellow et al, 1974) other herbivores (Noble, 1958) the patient had been in close association with cattle.

Described species:-

Sappinia diploidia


Gelman, B. B., Rauf, S. J., Nader, R., Popov, V., Borkowski, J., Chaljub, G. & Nauta, H. W. (2001) Amoebic encephalitis due to Sappinia diploidea., JAMA. 285, 2450-2451.

Goodfellow, L.P., Belcher, J.H. & Page, F.C. (1974). "A light- and electron-microscopical study of Sappinia diploidea, a sexual amoeba." Protistologica 10(2): 207-216.

Noble, G.A. (1958) Coprozoic protozoa from Wyoming mammals. J.Protozool. 5, 9-74.

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