Peculiar amongst their famously
celibate brethren, Sappinia is believed to be sexual
(Goodfellow et al,
A single case of amoebic encephalitis caused by an
amoeba identified on morphological grounds as being Sappinia
diploidea (Gelman et al, 2001).
This patient survived the infection having been treated with the
antibiotic azithromycin 250 mg/d for 31 weeks, pentamine 300 mg/d for
6weeks, intraconazole 200 mg twice daily and flucytosine 2.75g four
times a day. However, its not known if the patient would have
survived without the treatment. Sappinia has been isolatd
from faeces from cow (Goodfellow et al,
1974) other herbivores (Noble,
1958) the patient had been in close
association with cattle.
Gelman, B. B., Rauf, S. J., Nader, R.,
Popov, V., Borkowski, J., Chaljub, G. & Nauta, H. W. (2001) Amoebic
encephalitis due to Sappinia diploidea., JAMA. 285,
Goodfellow, L.P., Belcher, J.H. & Page, F.C.
(1974). "A light- and electron-microscopical study of Sappinia
diploidea, a sexual amoeba." Protistologica 10(2):
(1958) Coprozoic protozoa from Wyoming mammals. J.Protozool. 5,